High Ankle Sprain (Syndesmosis Injury): Causes, Symptoms, and Physiotherapy Treatment
- E-Young Khoo
- 4 days ago
- 4 min read
If you’ve twisted your ankle and the pain feels higher up, closer to the front of your lower leg rather than around the classic outer ligaments, there’s a good chance it’s not your standard ankle sprain. Instead, you might be dealing with a high ankle sprain, also known as a syndesmosis injury.
Unlike the common lateral ankle sprain, a high ankle sprain affects the tissues that sit between your tibia and fibula, the two long bones of your lower leg. These structures keep the ankle joint stable under load, and when they’re injured, walking, running, and changing direction can become extremely difficult.
This injury is especially common in athletes, but can happen to anyone.
What Is a High Ankle Sprain (Syndesmosis Injury)?
A high ankle sprain occurs when the syndesmosis ligaments, a group of strong connective tissues between the tibia and fibula, are overstretched or torn. The most important of these is the anterior inferior tibiofibular ligament (AITFL).
These ligaments stabilise the ankle when you twist, pivot, or push off forcefully. When injured, the two leg bones can separate slightly under load, which explains why weight-bearing is so painful.
While lateral ankle sprains involve rolling the ankle outward, high ankle sprains typically happen with external rotation of the foot or strong dorsiflexion (toes going upward under force).
How Do People Get a High Ankle Sprain?
Syndesmosis injuries often happen during high-force movements, especially in running and field sports. Common mechanisms include:
Typical Causes
Twisting the foot outward (external rotation) during a tackle or change of direction
Forceful dorsiflexion, such as landing awkwardly from a jump
Getting trapped under another player during sport
High-impact collisions in AFL, rugby, soccer, or basketball
Skiing accidents, where the boot locks the foot while the leg rotates
Everyday Injuries
While less common, non-sporting high ankle sprains can occur from:
Missing a step
Stepping into a pothole or uneven surface
Sudden, awkward twisting injuries
Because this injury involves deeper, stronger ligaments, it often indicates a more serious ankle injury than a regular sprain.
Common Signs and Symptoms
A high ankle sprain has a distinctive pattern of symptoms that helps differentiate it from more common ankle injuries:
Pain above the ankle joint, especially at the front
Pain when walking, particularly during toe-off
Difficulty weight-bearing or pushing off
Swelling that spreads up the lower leg rather than around the ankle
Pain with twisting or rotating the foot outward
Feeling of instability or “giving way” under load
Pain with calf squeeze tests or the “drive-through” syndesmosis test
Patients often describe the pain as a deep, sharp ache that flares with movement but may feel less severe at rest.
Physiotherapy Treatment for High Ankle Sprains
Because the syndesmosis stabilises the entire ankle joint, treatment must be structured, progressive, and more cautious than treatment for a normal ankle sprain.
1. Acute (Early) Management
Offloading or temporary immobilisation (moon boot or brace)
Reducing swelling with compression and elevation
Crutches if weight-bearing is too painful
Gentle pain-free activation of the calf and foot muscles
Avoiding twisting and pivoting movements
Physios will determine whether your injury is stable or unstable, which helps guide whether you need imaging, a boot, or orthopaedic review.
2. Mid-Stage Rehabilitation
Once pain settles and the joint is stable:
Strengthening the calf, peroneals, deep foot muscles, and tibialis posterior
Restoring mobility, especially dorsiflexion
Balance and proprioception retraining
Double-leg to single-leg loading
Introduction of controlled walking and gait retraining
This stage is crucial because poor mechanics here often lead to long-term instability.
3. Late-Stage Return to Sport / High-Level Function
For athletes or active individuals, final-stage rehab includes:
Jogging and running progressions
Plyometrics (hops, jumps, bounds)
Agility drills and sport-specific movements
Change-of-direction and acceleration work
Load testing to ensure the syndesmosis is stable during high force
A good physiotherapy program reduces the risk of chronic ankle pain and avoids the long-term complications that syndesmosis injuries are known for.
Differential Diagnosis: What Else Looks Like a High Ankle Sprain?
Medial and lateral ankle injuries can sometimes look similar, so a physiotherapist will rule out several conditions:
1. Lateral Ankle Sprain
Pain on the outside of the ankle
Often from rolling the ankle inward
Swelling is more localised
2. Medial Ankle Sprain
Pain around the deltoid ligament on the inside of the ankle
More likely with eversion injuries
3. Distal Fibula Fracture
Bone tenderness on the outer lower leg
Pain with any weight-bearing
Must be ruled out if swelling is severe
4. Osteochondral Lesion of the Talus
Deep joint pain, catching, or clicking
Often coexists with ankle sprains
5. Peroneal Tendon Injury
Pain behind or below the outer ankle bone
Worse with side-to-side movement
6. Calf Tear (Especially Soleus)
Pain when pushing off
Can mimic syndesmosis symptoms in early stages
This is why early assessment by a physiotherapist is essential, getting the diagnosis wrong can lead to delayed recovery or chronic ankle instability.
A high ankle sprain (syndesmosis injury) is one of the most misunderstood ankle injuries because symptoms can be subtle initially but debilitating long-term. Fast, accurate diagnosis and structured physiotherapy treatment are the key to preventing ongoing ankle pain, instability, and delayed return to sport.
If you’re dealing with pain above the ankle, difficulty weight-bearing, or pain when twisting the leg, a physiotherapy assessment can help you get clarity and start proper rehabilitation immediately.
If you're dealing with any of these symptoms. Book with Urban Physiotherapy today! - https://urban-physiotherapy.au2.cliniko.com/bookings?business_id=423637795941128200#service



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